Regul Toxicol Pharmacol 96:127134 Iskandar AR, Titz B, Sewer A, Leroy P, Schneider T, Zanetti F, Mathis C, Elamin A, Frentzel S, Schlage W, Martin F, Peitsch MC, Hoeng J (2017) Systems toxicology meta-analysis of in vitro assessment studies: biological impact of a modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the respiratory tract
A since 1975
JTI in 2013 nevertheless introduced its proprietary Ploom device, a heat-not-burn tobacco product, on a trial basis in six markets, including Japan (the others are Austria, France, Italy, Korea, and the UK)
These cigarettes mimic the experience of smoking without the addictive chemical